Hey guys, great forum. I was respectfully hoping for any constructive thoughts about my first year with trt. My insurance surprisingly covered efforts thus far so I am within the limitations of my local Low-T clinic. Want to graduate to Self medicating asap. Longer story shorter, I started last September testing below 300 total test. I was given 140mg/wk. That raised my tt to 520. Dose was raised to 190/wk. This raised tt 715. E2=36 shbg=40. Dose raised to 200mg/wk. Did my own sensitive e2 in January, read 73.1 started .5mg anastrazole a week 48hrs post shot. By March things were going the wrong direction at tt=407 e2=31.0 shbg=41.3 Increased dose to 220mg/wk. April readings were T=525, E=37.2 shbg=34.2 Increased to 250mg/wk. August had tt=518. Increased to 270mg/wk at present. These doses seem really high and concern me as to general health repercussions. And my test readings are not reflecting the increases really. I see sporadic comments about "hyper metabolizers". Is anyone successful long term with this high of doses? Any recommendations from you veterans? Any constructive thoughts appreciated.