Thyroid & Neurotransmitters I thought this might generate some interesting discussion: I am hypothyroid. I also used to wake with night sweats. I saw a physician who indicated that the night sweats were the result of being hypothyroid causing. The theory is that I have a mitochondrial issue where my mitochondria do not readily using the thyroid that is present. Body temperatures naturally drop a little at night when people sleep. In my case, the additional drop in temperature caused my Norepinephrine to dramatically increase in an attempt to keep my body temps from going too low. The increased Norepinephrine would cause the sweating. It was also the cause of my waking up, since Norepinephrine is stimulating and can increase blood pressure, heart rate, etc. Granted urine labs do actually measure the amount of neurotransmitters in the brain, but the labs I did seemed to support the theory. The doctor said that my Serotonin and Dopamine were about half of what one would expect and my Norepinephrine was sky high. I gradually increased my Armour dosage to where I am now at 5 grains a day. I also take 25mg of Iodoral per day. The night sweats are now pretty rare and I my sleep seems to be deeper and more restful. My body temperature, however, remains a little low (average 96.5 or so). I have read where doctors who agree with the practices of Broda Barnes, M.D. and Mark Starr, M. D. pretty much believe that labs should not be the main guide when prescribing Armour. Rather relief of patients’ symptoms should be the guide. It made sense to me that if I did indeed have mitochondrial issues, then I could very well still have hypothyroid symptoms, even though my labs indicated that was not the case. Anyway, when my PCP recently was doing my routine labs, I asked him to check my thyroid levels. Unfortunately, he did not do free T3 or T3 at all for that matter. Here are the results: TSH <0.01 (0.35 – 5.50) Total Thyroxine (T4) 10.4 (4.5 – 12.0) Free T4 2.09 (0.70 – 1.53) T3 Uptake 44 (24 -39) Free Thyroxine Index 4.6 (1.2 – 4.9) I shared the results with the doctor who prescribes the Armour. He indicated that using TSH to indicate whether or not someone has too much thyroid hormone is like using LH as an indication of whether someone has too much Testosterone. On a side note, I have been prescribed 40mg of Test twice per week. I am also prescribed 250IU of HCG on those days, but lately finding that has been pretty impossible to find in my neck of the woods. I live in the sticks.