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Kjellfh`s Journal - Low T and/or other problems

Discussion in 'Member Journals' started by kjellfh, Aug 23, 2014.

  1. kjellfh

    kjellfh Member

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    Hello. My first post got deleted for some reason.
    So I start over again.

    26 year old male,
    height: 170cm / 5,5 ft,
    weight: 67kg / 147.5 lbs.

    Problems with low testosterone for around 3 years. I think bad sleep combined with overtraining and negative stress over a longer period maybe started some of this, but don't know for sure. When I had the lowest numbers, I practiced a fairly high amount of cardio and a little resistance training. Had been doing this for quite some time.
    I have quit all mid-high exercise long time ago and are a more mentally robust person at this time. Done a lot of CBT(still doing) and counseling. Eliminated most stressors in my life and try to take things at my own speed. Are doing some light exercise(walking/swimming/yoga) and get a fair amount of light physical activity in my job. Life quality is better but still I have failed to see any results in terms of symptom relief, it has gradually been getting worse.

    Sleep hygiene is good:
    Go to bed same time every day, out in sunlight every day, cold room, completely dark, fresh air, no EMFs, earthing mat, blue block glasses and audio books/chants/binaural beats if not getting to sleep or waking up.

    Relevant tests/info:
    No problems with puberty.
    Never used steroids or similar substances.
    Done multiple MRI`s with contrast, pituitary is ok.
    Done spinal tap twice, a little high in inflammatory cells the first time, second was all ok.
    Checked for borrelia.
    Checked for sleep apnea.
    Checked for HIV and Hepatitis.
    Liver tests have been ok all the way.
    No other disease I know of that could be related.
    Full lipid panel taken mid august 2013 was fine, little low in omega 3 despite supplementation/eating fish.
    Done LgG urine/and blood test, this showed intolerance to casein and some to gluten.
    Done a gene test at 23andme.com, this show a homozygous MAO-A R297R, all results:
    View attachment Genetic_Genie_Detox_Profile.pdf
    View attachment Genetic_Genie_Methylation_Profile.pdf .

    Diet:
    Varied. No calorie restriction, lots of healthy fats(olive, coconut, macadamia, avocado, ghee), all kinds of vegetables, low/medium glycemic carbs, meat ,fish, eggs and some nuts, berries and fruits. No/very little refined/processed foods. Stopped gluten and casein for half a year ago. Keep myself away from phyto and xeno-estrogens. No regular supplements. No alcohol, nicotine or other stimulants.

    Current symptoms/observations:
    - Really bad sleep (waking up many times, waking up early and cannot get back to sleep, waking up feeling unrested/like garbage).
    - Night sweats (followed me from the start, had some better periods sometimes).
    - Hot flashes/feeling warm now and then during daytime.
    - More body fat(especially abdominal) and minor gyno development.
    - Very low libido (been with me from the start, got better when on TRT).
    - Poor concentration.
    - Bad mood and depression.
    - Anxiety, come and go with no obvious reason.
    - Very sore and stiff after exercise/physical activity.
    - Weight before bedtime is typically 1.5-3.0 kgs (3.3-6.6 lbs) heavier than in the morning.
    - Higher resting pulse than before(was between 50-60, now 60-80),
    - Cannot tolerate caffeine or other stimulants(chocolate/theobromine, tobacco/nicotine, alcohol) anymore,I get headache, high pulse and BP, sometimes anxiety and generally feel bad.
    - Rarely feel satiation after meals, sometimes I can eat what seems to be endlessly (this have been with me from the start).
    - Had a trial with high dose phosphatidylserine and I felt really good for a couple of days, however this effect disappeared and I haven't had the same success with it later(tried both low and high doses at different times a day with no effect)..
    - Nasal congestion at bedtime (lately).
    - Inconsistent and rare stool frequency.
    - I am very rarely "real" sick (fewer, runny nose, coughing, nausea or stomach aches). Gets the flu maybe once a year.
    - Melatonin worked for sleep to begin with, now I get paradoxical reaction(more awake) or no effect at all.
    - Excessive thirst/urination, especially at evening/night and in the morning.

    Some good input from the original thread:
     
    Last edited: Dec 14, 2014
  2. kjellfh

    kjellfh Member

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    History/blood tests:

    05.10.2012, went to the doc because of issues with sleep, headaches and libido that had disappeared completely. My GP ran a number of tests and said all came back fine except for little low testosterone.

    05.10.2012, first blood test:
    CRP - <1.0 (0.00-5.0) mg/L
    HGB - 13.2 (13.4-17.0) g/dL
    TSH - 1.9 (0.30-4.2) mlE/L
    FT4 - 11.5 (11.0-22.0) pmol/L
    TESTOSTERONE - 4.7 (9-35) nmol/L
    PROLACTIN - 134 (100-400) mlE/L

    05.25.2012, was instructed to take another test:
    ESTRADIOL - <0.05 (0.00-0.16) nmol/L
    TEST - 2.1 (9.0-35.0) nmol/L
    SHBG - 69 (15-85) nmol/L
    FSH - 6.8 (1.0-12.0) IE/L
    LH - 2.6 (1.0-10.0) IE/L
    PROLACTIN - 271 (100-400) mlE/L

    06.19.2012, another test done(dont know if this is relevant):
    HGB - 12 .8 (13.4-17.0) g/dL
    FERRITIN - 34 (30-400) µg/L
    B12 - 338 (150-700) pmol/L
    CRP - 17 (0.00-5.0) mg/L
    CORTISOL - 461 (220 - 850) nmol/L

    09.11.2012, after long time waiting I was finally to see an endo. He could not explain why my T was low. I was sent to take more tests:
    TESTOSTERONE- 4.0 (9.0-35.0) nmol/L
    ESTRADIOL <0.05 (0.00-0.16) nmol/L
    CORTISOL 536 (220 - 850) nmol/L
    FT3 3.7 (3.1-6.8) pmol/L
    FT4 12.2 (11.0-22) pmol/L
    TSH 1.1 (0.30-4.2) mlE/L
    GLUCOSE 5.3 (4.0-6.3) mmol/L
    HbA1C 4.9 (4.0-6.0) %
    SHBG 45 (15-85) nmol/L
    FSH 7.8 (1.0-12.0) IE/L
    LH 1.0 (1.0-10.0) IE/L
    PROLACTIN 155 (100-400) mlE/L
    17-hydroxy progesteron Normal(?)
    IGF-1 41 nmol/L.

    11.02.2012, endo told me to take more tests:
    Free TT index 1.92 (3,0 – 14,7)
    ACE Normal(?)
    FSH 9.8 (1.0-12.0) IE/L
    LH 2.6 (1.0-10.0) IE/L
    TEST 10 (9.0-35.0) nmol/L
    SHBG 52 (15-85) nmol/L

    Endo then set me on T-Gel(Tostran 2%) in late November 2012. He instructed me to apply the gel on my chest and stomach. Was on it for about 4 months(50mg ED), after a while I got a little better sleep and some libido from time to time but nowhere near how it was before this started. Also developed some gyno. My endo said I should continue on this regime the rest of my life and that that my problems had to come from psychological reasons. He could not explain gyno though, once again he told me that steroid use would have explained it all.

    02.04.2013, blood test taken after about 2 months on gel:
    Free TT index 3.20 (3,0 – 14,7)
    TESTOSTERONE - 12.3 (9.0-35.0) nmol/L
    SHBG 38 (15-85) nmol/L
    FSH 1.9 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L
    HGB 14.4 (13.4-17.0) g/dL
    PSA 0.3 (0.00-2.5) ug/L

    02.22.2013, blood test taken after almost 3 months on gel:
    Free TT index 4.97 (3,0 – 14,7)
    TESTOSTERONE - 14.4 (9.0-35.0) nmol/L
    SHBG 29 (15-85) nmol/L
    ESTRADIOL 0.11 nmol/L
    HCG <2 IE/L <3 IE/L
    FSH <0.5 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L
    17-hydroxy progesteron 2.7
    FT4 11.8 (11.0-22) pmol/L
    TSH 1.7 (0.30-4.2) mlE/L

    Went to another endo early in April who set me on Nebido injections(Testosterone undecanoate 250mg) 8 weeks apart. I had a couple of weeks where I actually felt very good after the first injection. This feeling disappeared and I then experienced a rollercoaster trip downwards. The second injection I didn't feel at all. I can remember waking up having some nocturnal wood a couple of times but that was all. Had a trial of low dose Arimidex mid/late in second injection. Didn't notice anything other than losing some weight(maybe water?).


    04.30.2013, blood testtaken about 3 weeks after first injection:
    TESTOSTERONE 26.4 (9.0-35.0) nmol/L
    SHBG 57 (15-85) nmol/L
    ESTRADIOL 0.06 (0.00-0.16) nmol/L
    FSH <0.5 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L

    06.03.2013, blood tests taken about 8 weeks after first injection:
    TESTOSTERONE 12.3 (9.0-35.0) nmol/L
    SHBG 36 (15-85) nmol/L
    FSH <0.5 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L
    PROLACTIN 99 (100-400) mlE/L

    06.05.2013, took the second shot of Nebido.

    07.29.2013, blood test taken about 7 weeks after the second shot:
    TESTOSTERONE 15.1 (9.0-35.0) nmol/L
    SHBG 41 (15-85) nmol/L
    TSH 1.4 (0.30-4.2) mlE/L
    FSH <0.5 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L
    FERRITIN 175 (30-400) µg/L

    07.31.2013, Started with Clomid 50mg ED(about 8 weeks after the second Nebido injection). Got the vision sides after awhile, cut down dosage to 25mg ED. At the time I started Clomid, my balls had shrunk pretty much, after the use of clomid they have seem to regain some(if not all) of their size. Did not feel any better while on clomid, like before I started, maybe even worse. Gyno also got worse at the end.

    08.14.2013, after two weeks on 50mg clomid :
    Free TT index 3.70 (3,0 – 14,7)
    TESTOSTERONE 14.0 (9.0-35.0) nmol/L
    SHBG 38 (15-85) nmol/L
    ALBUMIN 50 (36-48) g/L

    08.19.2013, first blood test 20 days after starting with clomid 50mg ED:
    TESTOSTERONE - 15.2 (9.0-35.0) nmol/L
    SHBG - 42 (15-85) nmol/L
    ESTRADIOL - <0.05 (0.00-0.16) nmol/L
    FSH - <0.5 (1.0-12.0) IE/L
    LH - <0.5 (1.0-10.0) IE/L
    TSH - 2.3 (0.30-4.2) mlE/L
    FT4 - 11.5 (11.0-22) pmol/L
    PROLACTIN - 159 (100-400) mlE/L
    GLUCOSE - 5.3 (4.0-6.3) mmol/L
    HbA1C - 5.0 (4.0-6.0) %
    PSA - 0.43 (0.00-2.5) ug/L
    HGB - 15 (13.4-17.0) g/dL

    12.16.2013, on clomid 25mg ED since November:
    TESTOSTERONE - 12.6 (9.0-35.0) nmol/L
    SHBG - 49 (15-85) nmol/L
    ESTRADIOL- <0.05 (0.00-0.16) nmol/L
    FSH - 6.8 (1.0-12.0) IE/L
    LH - 1.9 (1.0-10.0) IE/L
    TSH - 1.2 (0.30-4.2) mlE/L
    FT4 - 11.2 (11.0-22) pmol/L
    GLUCOSE - 4.9 (4.0-6.3) mmol/L
    HbA1C - 4.7 (4.0-6.0) %
    CRP - <1.0 (0.00-5.0) mg/L
    PSA - 0,32 (0.00-2.5) ug/L
    HGB - 13.3 (13.4-17.0) g/dL

    01.03.2014, my new general doctor ran many tests, here are some of them:
    TESTOSTERONE - 10.0 (9.0-35.0) nmol/L
    SHBG - 46 (15-85) nmol/L
    TSH - 2.4 (0.30-4.2) mlE/L
    FT4 - 12.8 (11.0-22) pmol/L
    ALBUMIN - 52 (36-48) g/L
    FOLATE - 31.7 (7.7-25)
    B12 - 553 (150-700) pmol/L
    HGB - 14.0 (13.4-17-0) g/dL
    Vitamin D - 57 (37-131) nmol/L

    03.24.2014, recently quit clomid:
    TESTOSTERONE - 19.0 (9.0-35.0) nmol/L
    SHBG - 46 (15-85) nmol/L
    ESTRADIOL- 0.05 (0.00-0.16) nmol/L
    FSH - 12.9 (1.0-12.0) IE/L
    LH - 4.9 (1.0-10.0) IE/L
    TSH - 1.4 (0.30-4.2) mlE/L
    FT4 - 11.6 (11.0-22) pmol/L
    PROLACTIN - 119 (100-400) mlE/L
    GLUCOSE - 5.1 (4.0-6.3) mmol/L
    HGB - 13.3 (13.4-17.0) g/dL
    HbA1C - 5.3 (4.0-6.0) %
    HAEMATOCRIT - 0.40 (0.40-05.0)

    Despite the higher readings, I didn't feel any better or different this period.
    05.22.2014,
    TESTOSTERONE 7.8 (9.0-35.0) nmol/L
    SHBG 49 (15-85) nmol/L
    ESTRADIOL 0.05 (0.00-0.16) nmol/L
    FSH 8.0 (1.0-12.0) IE/L
    LH 2.0 (1.0-10.0) IE/L
    PROLACTIN 90 (100-400) mlE/L
    CHOLESTEROL 5.5 (4.0-6.0) mmol/L
    HDL 2.0 (0.8-2.1) mmol/L
    LDL 3.3 (1.3-4.3) mmol/L
    HbA1c 5.0 (4.0-6.0) %

    07.01.2014,
    HEMOGLOBIN 13.7 (13.4-17.0) g/dL
    PSA 0.29 (0.00-2.5) ug/L
    ESTRADIOL <0.05 (0.00-0.16) nmol/L
    TESTOSTERONE 11.6 (9.0-35.0) nmol/L
    SHBG 40 (15-85) nmol/L
    FSH 9.6 (1.0-12.0) IE/L
    LH 3.1 (1.0-10.0) IE/L
    PROLACTIN 159 (100-500) mlE/L

    07.11.2014,
    CORTISOL 466 (220-850) nmol/l
    TESTOSTERONE 14.4 (9.0-35.0) nmol/L
    SHBG 42 (15-85) nmol/L
    PROGESTERONE 1.8 (<3) nmol/L
    DHEAS 6.0 (3.4 – 17.0 µmol/L)
     
  3. kjellfh

    kjellfh Member

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    Got prescription for Pregnyl(HCG) and Gonal-F (FSH/follitropin alfa) from my endo when he was back from vacation. Started on HcG 250IU EOD subq Tuesday this week. I don`t think I have much to loose doing this?
    I have no plans on trying Gonal-F yet as it is very expensive and I don't find much information about it. Any opinions?

    I have ordered some Bacteriostatic water because the mixing agent that follow the Pregnyl version I have is standard NaCl water only.
    Anyone know the shelf/fridge life of HcG mixed with the accompanying NaCl in a sterile vial by the way?
    I have to use this until the BAC water arrives.

    With help from a private doctor I took some final tests before I started HcG, these tests included cortisol saliva 2x. I asked for 4x but that is not common here and seemed difficult to get.
     
    Last edited: Aug 23, 2014
  4. JanSz

    JanSz Well-Known Member

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    Note that you talk about erections only when your estradiol is at its reported highest.
    Do not ruin your chances using Arimidex.

    It looks like your testicles are not making enough testosterone.

    Nebido® One ampoule contains 1000 mg of testosterone undecanoate in 4 ml of oily vehicle.

    You have very high SHBG, low testosterone, low estradiol, unknown levels of DHT.
    Your Hgb and HCT are rather lowish, that is good news considering the above.

    High SHBG binds most of any available testosterone.
    It is possible to manipulate SHBG. You may get it lower by having higher Total Testosterone.
    You would have to explain that to your prescribing doctor.
    May want to start with 200mg/week on average, that would be 1000mg Nebido injection every 5 weeks.
    1000/5=200
    You can stay on that dose indefinitely or till your SHBG stabilizes at (15-20)
    Or just stay on 5 weeks frequency as long as SHBG is at 15 or higher.

    Nebido is long acting and it takes long time to stabilize, so do not make hasty decisions.
    Other than SHBG you may want to monitor E2, DHT, progesterone, cortisol & Hgb.
    To have erections you not only need good FreeTestosterone levels but also E2 and DHT.

    One may get gyno if E2 is not controlled by sufficient progesterone level.

    Higher testosterone levels helps in keeping better Hgb & HCT levels. Yours are rather low now.
    While on supplemental testosterone it is always good practice to monitor iron indicators and Hgb & HCT.

    Pregnyl(HCG) and Gonal-F (FSH/follitropin alfa)

    We use HCG for two reasons.
    "Normal" doses to keep some testosterone production and (mainly) to keep scrotum and testicles from atrophying, also to get some E2.
    Litle higher HCG doses may be used to raise E2.

    Gonal-F (FSH/follitropin alfa), HMG, or other forms of FSH are used in pregnancy protocol, to raise otherwise low sperm.


    /////////////////
     
    Last edited: Aug 25, 2014
  5. Picton

    Picton Super Moderator Staff Member Super Moderator

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    This is why some of us FREEZE syringes of prepared doses of HCG.
     
  6. kjellfh

    kjellfh Member

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    Thank you so much for valuable input again JanSz.

    If I fail to see success with HcG only i will consider adding Nebido or Tostran(2% gel).
    Is the castor oil that nebido comes with ok to set subcutaneously?

    So I will not have any other benefit than better/higher sperm count of using Gonal-F/FSH?
    I`m not trying to make anyone pregnant and have no plans of this in the near future either.
     
  7. kjellfh

    kjellfh Member

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    If this works, maybe I just should do that. Thanks for the tips.
    Is there any information regarding shelf life on this method? Do I need to have some airspace inside the syringe due ice expanding?
     
  8. JanSz

    JanSz Well-Known Member

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    With HCG only, at the most, you may expect natural testosterone levels.
    You have a high SHBG.
    The dosing that I was proposing ************ should put your TT at higer that natural levels, and hopefully would get your SHBG lower.

    Nebido comes in 4mL ampoules.
    If you inject it all at once, it would have to be IM shot with long needle.
    Doctors often want that shot to be done in their office.
    For good start-up it would be good to get first shot in the doctor's office.
    To not complicate procedure and to see if it is beneficial to you, you may want to stick with shots at doctor's office for at least 6-9 months.
    The monitoring and any dose adjustments I envision as primarily via monitoring SHBG level, and testosterone levels may be monitored or not.

    SHBG levels depend on T (high T pushes it down), E2 (high E2 raises it), and, good thyroid panel and good GH, IGF-1, IGFBP3, stabilizes SHBG at good levels.


    ...
     
    Last edited by a moderator: Aug 26, 2014
  9. Mikluz

    Mikluz Member

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    i've done it too and never had any problems with preparing HCG shots for the next couple of weeks. i tried both leaving some airspace and pushing all air out before putting to freezer and never really noticed any difference.
     
  10. Picton

    Picton Super Moderator Staff Member Super Moderator

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    Yes, I certainly leave a tiny extra amount... in effect I also don't work to get the air out when I fill them, I find the air is easier to get out (for some reason!) too once they have thawed - this only takes a few minutes, or warm the syringe in your hand and it is even quicker.

    I tend to use 10,000iu vials if I can get them, for reasons of cost and as I only use 200iu per dose that's near enough 50 syringes (bit of a chore to fill!) less a few for wastage - don't do what I did once, that is use sterile water, it stings! Sterile saline doesn't hurt at all.

    I don't notice any deterioration of potency at all unlike when using Bacteriostatic water and refrigerating.
     
  11. kjellfh

    kjellfh Member

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    Update:

    Been on HCG 250 IU subcutaneously every other day since 08.19.2014. I have found the freeze method is nice when it comes to storing/handling. I have not had any problems with the injections so far. I am using BD micro fine insulin needles (0.3 mm / 30G x 8mm).

    Tried to go off Mianserine/Tolvon(similiar to Mirtazapine) late august but failed, been on 10-60 mg for sleep since 07.11.2014. It have lost much of its initial effect but still helps a little bit. My doctor says I should wait to cease this medication to my hormones/symptoms are better. This is the only medication I take regularly now (besides HCG).

    Couldn't handle work anymore due sleep and other issues so I have been reported sick since 08.25.2014. So all my focus is now on getting better with absolutely no outside stressors.

    Were at a follow up consultation at my GP on 09.05.2014. It just so happens that I showed him a eczema that I have had for a long time but that never bothered me/paid any attention to. I was told this probably were Erythema-Migrans - a sign of lyme disease/borrelia infection. Was prescribed antibiotics(Doxylin 100mg x 2 ED) right away and was told to take this for 14 days.
    I hope that maybe some of my problems is related to this infection and that I can get rid of the whole thing with the antibiotics.

    Been trying to do all the right things like before; healthy diet, long walks, yoga/meditation, light therapy, cold baths/showers, good sleep hygiene etc. but not seen any consistent improvement. Been only 3 weeks on HCG and 5 days on antibiotics, so I don't know if I should expect anything yet?

    Got some blood test results from last month today, these were taken the same day(before) I started with HCG monotherapy and was ordered by a private doctor. I have included everything that I have received results on so far. I will ask for LH and any other remaining results when I have consultation with him at 09.16.2014.
    Tests taken 08.19.2014:

    HEMOGLOBIN 14.4 (13.4-17.0) g/dL
    MCH 29 (27-33) pg
    FERRITIN 235 (30-400) μg
    VIT B12 581 (150-700) pmol/L
    FOLATE 41.7 (7.7-25.0) nmol/L
    HOMOCYSTEINE 11 (3-15) μmol/L

    FASTING GLUCOSE 5.3 (4.0-6.3) mmol/L
    HbA1c 5.1 (4.0-6.0) %

    CRP <1.0 (0.00-5.0) mg/L
    ALBUMIN 51 (36-48) g/L

    CHOLESTEROL 5.5 (2.9-6.1) mmol/L
    HDL 1.6 (0.8-2.1) mmol/L
    LDL 3.8 (1.3-4.3) mmol/L
    TRIGLYCERIDES 0.84 (0.45-2.60) mmol/L

    CREATININE 78 (60-105) μmol/L
    Pt-GFR >60 (?)
    URIC ACID 332 (230-480)
    μmol/L

    GT 14 (10-80) U/L
    ALAT 14 (10-70) U/L

    POTASSIUM 4.3 (3.5-4.4)
    mmol/L
    CALCIUM 2.46 (2.15-2.51) mmol/L
    CALCIUM CORR. 2.27 (2.17-2.47)
    mmol/L
    MAGNESIUM 0.82 (0.71-0.94)
    mmol/L
    ZINC 14 (10-17) umol/L
    SELENIUM 1.1 (0.6-1.8)
    umol/L

    TSH 3.2 (0.30-4.2) mIE/L
    FREE T4 11.3 (11.0-22.0) pmol/L
    FREE T3 5.2 (3.6-8.3) pmol/L
    DHEAS 5.6 (3.4-17.0) μmol/L
    ESTRADIOL <0.05 (0.00-0.16) nmol/L
    PROGESTERONE 2.4 (?) nmol/L
    S-17-OH PREGNENOLONE 17.0 (<26) nmol/L
    TESTOSTERONE 10.9 (9.0-35.0) nmol/L
    FREE TT INDEX 2.5 (3.5-9.3)
    SHBG 43 (15-85) nmol/L
    HCG <1 (<3) IE/L
    FSH 6.8 (1.0-12.0) IE/L
    PROLACTIN 234 (100-400) mIE/L

    S-25-OH-VITAMIN D3 83 (37-131) nmol/L

    CORTISOL SALIVA 23:15/NIGHT <6.0 (<6.0) nmol/L
    CORTISOL SALIVA 07:40/MORNING 31.4 (<27) nmol/L

    What i see:
    MORNING CORTISOL is elevated, but not much?
    FOLATE and ALBUMINE is elevated and have also been elevated numerous times before,
    I do not know what that means, I do not take any folate supps. or other vitamins/supplements, but eat a lot of vegetables.
    HOMOCYSTEINE is kind of high? This has also been high before.
    Is DHEAS levels low?

    Should I be concerned of any of this? Any input is appreciated.
     
    Last edited: Sep 30, 2014
  12. kjellfh

    kjellfh Member

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    34 days with HCG 250 IU EOD.

    09.22.2014
    morning:
    HEMOGLOBIN 13.4 (13.4-17.0) g/dL
    HAEMATOCRIT 0.41 (0.40-05.0)
    MCH 29 (27-33) pg
    PSA 0.40 (0.00-2.5) ug/L
    ESTRADIOL 0.07 (0.00-0.16) nmol/L
    TESTOSTERONE 18.2 (9.0-35.0) nmol/L
    SHBG 38 (15-85) nmol/
    FSH 2.6 (1.0-12.0) IE/L
    LH <0.5 (1.0-10.0) IE/L
    PROLACTIN 506 (100-400) mlE/L

    Waiting for some other tests taken 09.17.2014, but haven't got them yet.

    Took new spinal fluid/lumbar puncture tests 09.22.2014, this were all normal (no borrelia/lyme).

    I have not noticed any big difference after the antibiotics treatment or since last update. Paradoxically I got a throat infection right after I started on the antibiotic. This maybe set me back a little on the progress of getting better. Been two weeks since that now so this should not interfere anymore.

    I am experiencing much of the same "pattern" as before with a day once in a while that are ok and most beeing not good. Could be that I have some less intense hot flashes/night sweats than before but not sure. Also noticed some nipple itching/sensitivity when waking up at night, cant remember this from earlier.

    My endocrinologist instructed me to take new tests three months from now and just keep on the same dosage(his recommended dose was 2000IU three times a week) I have not followed this regime and I don't think that I will either.

    Any thoughts ?
     
    Last edited: Sep 30, 2014
  13. Picton

    Picton Super Moderator Staff Member Super Moderator

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    As well as some of the more obvious things highlighted, it screams Low magnesium to me which is guaranteed poor sleep! And don't I know it myself! :-(

    Some good info:
    http://www.drmyhill.co.uk/wiki/magnesium_-_treating_a_deficiency

    I personally favour Magnesium chloride (try ebay!) either orally or arguably better transdermally.

    Similarly, your Vitamin D levels are far too low too, no surprise from the Northern latitude you live at!
    If you supplement vitamin D3...then make sure you ALSO supplement vitamin K2 (NOT vitamin K) to ensure your calcium stays in your bones and not your bloodstream!) lots of info to be found online.

    Your thyroid levels are not exactly optimal either... (might account for higher than ideal SHBG?) Magnesium should do no harm in that respect either, (and other minerals etc see http://www.thyroiduk.org.uk/tuk/treatment/vitamins.html ) although don't go on to thyroid supplementation until you get your Cortisol issues sorted.

    One off high prolactin isn't something to panic about, as lots of things can cause that.
     
  14. kjellfh

    kjellfh Member

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    I have tried long term supplementation of magnesium numerous times earlier. Now I only use it occasionally for sleep as it looses its effect very quickly if I use it regularly. I have used chloride, citrate, malate and chelate(glycinate). I have also tried warm baths with 2 cups of magnesium sulfate regularly over time.

    When I use it now it is in the glycinate/chelate form at 200-600mg.Never noticed any other benefit other than it sometimes help me get back to sleep when I wake up at night.

    Test from 08.19.2014 shows MAGNESIUM 0.82 (0.71-0.94) mmol/L within range, I have taken magnesium tests numerous times earlier, also within range.

    I take solarium regularly to help with Vitamin D and compensate for the winters here, also eat some fish and butter which are rich in vitamin D, so I don't understand if it is low. Vitamin D has been much lower earlier.

    I will check out the links you gave me, thanks.

     
  15. kjellfh

    kjellfh Member

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    Woke up with itchy breast/nipples again last night. Should I be worried about gyno getting worse? Is there any other signs of high E i should look out for? Had some nightmares but slept fairly well overall. Thinking of going to daily injections of 125 or 150 IU.
     
    Last edited: Oct 1, 2014
  16. Picton

    Picton Super Moderator Staff Member Super Moderator

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    You don't want "in range" or "normal" you want OPTIMAL which is often significantly more. If your test was within 7 days of supplementing, it might not even represent an actual base level!
    The best test is magnesium RBC (red blood cell) test but not always easy to get everywhere :-(

    Vitamin B6 is supposed to help it absorb.

    I fond Epsom Salts baths were very pleasant, and fairly effective but used a ridiculous amount of the stuff, and I left white marks everywhere i went!

    Whilst Magnesium is just low, your Vitamin D is positively borderline, http://www.medscape.com/viewarticle/589256_7

    I found it difficult to get Vit D3 up even using 10,000iu per day for a long time, and I too eat a lot of dairy, it's not easy, and I live a bit south of you! Even now I am still well within the top of the range on a maintenance level of 5,000iu daily.

    Interestingly I now find my calcium is not very high even though I subsist eating dairy, so eating it is not all it's cracked up to be!

    Magnesium and Vit D3 were the two single things that as had most noticeable effect on my own well being, far more so than Testosterone ever had!
     
  17. Picton

    Picton Super Moderator Staff Member Super Moderator

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    Your last E2 figures weren't particularly high though were they? Correct me if I am wrong, that's 70 pmol/l (used in UK), so that should be 25 in US units?
    (of course Progesterone levels/ratio (to E2) can be related to Gyno too)
     
  18. JanSz

    JanSz Well-Known Member

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    Also wonder about this

    PROLACTIN 506 (100-400) mlE/L

    latest known event, while previous tests indicated rather low prolactin.



    ...
     
  19. Picton

    Picton Super Moderator Staff Member Super Moderator

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    Good point, but a one off can be caused by a number of things..... (worth looking up) and it might be wise to avoid stimulating situations before a retest
     
  20. kjellfh

    kjellfh Member

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    A LHRH and TRH test is scheduled for 12.01.2014. I am instructed to quit Pregnyl/HCG two weeks before the tests. My question is: can I take testosterone gel insted of HCG this time? Or will this also interfere with the tests?
     

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