Recently, I started HCG with my TRT. I was hoping it would give me quite a boost. Unfortunatly it did not. My starting test value was over 500, after one month on HCG my test value was 220. I started at a dose of 400IU E3D. After I recieved my blood test, I increased my dosage to 500IU EOD. I was actually having bad sides. My sex drive went away, ED, the boys got smaller, and lack of all motivation. Felt pretty bad. Checked my E2 and it was still under 20. The brand I was using was Hucog. This was the stuff before they switched over to the pre mix. I mixed it correctly with bacteriostatic water and kept it in the fridge. I think it was legit because my LH and FSH numbers tanked on the second blood test. I was thinking about trying Novarel but it is much more costly. Has anyone ever heard of someone not responding to HCG? Any insight would be appreciated.