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Official Finasteride Thread

Discussion in 'Post-Finasteride Syndrome & Accutane Sufferers' started by Dr. John Crisler, Jun 23, 2009.

  1. Took_accutane

    Took_accutane Member

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  2. Jaydee

    Jaydee Member

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    Here is something that I think is VERY interesting.

    There is such a thing called a candida spit test. Whether or not this test is indicative of a problematic yeast infection is debatable. What we do know is what yeast looks like. It's long and stringy when put in water.

    For some time now, I have strongly suspected that my ejaculate has been FULL of yeast. It looks really "stringy" and pathonogenic (if that's a word).

    So I ejaculated into a glass bottle half filled with water to see if it looked the same as my spit test and guess what? Exactly the same except the stringy bits look really well developed.

    There is at least one guy on the propeciahelp forum who fully recovered mainly due to taking Nystatin and he blamed his PFS on bad lifestyle and candida.

    I also have a plethora of other candida infection symptoms and a history of extreme anti-biotic use and I've also been told I have systemic candida due to live blood analysis. I also have a history of ingesting large amounts of dextrose when weight training to try and keep my weight on.

    I also found this peice of information from a Dr who specialises in candida treatment where he says "candida in the tissue somehow inhibits the tissue from responding normally to hormones. "

    Here's the link:

    http://www.angelchiro.com/candida.htm


    I wonder if we could get in contact with this doctor and discuss PFS with him?

    I wonder if Dr Crisler would like to pick his brain a bit?:thumbup:
     
  3. Jaydee

    Jaydee Member

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    Further to my last post regarding Candida, I'm the fellow who got instant recovery from doing a colon cleanse, though it was only temporary (about 2 hours).

    I think it was the day after the colon cleanse or could have been that night, my libido was THROUGH THE ROOF. It was all systems go. Best libido I've ever had in my life and this was while I had PFS. I noted that when the feces were going through the clear tube during the colon cleanse, it looked like long stringy bits in the feces that were coming out and I'm almost certain the lady said it was candida. Sorry to be so graphic but I really think it's relevent.

    That is the ONLY time I've had libido since taking finasteride. But also just prior to taking finasteride I was put on a MAJOR stretch of antibiotics that had to be imported from the US, they were VERY strong to combat a stomach clostridium infection. It was a short while after those antibiotics that I started getting PFS. I also had unprotected sex and caught what I believe was a very nasty case of thrush off a woman at around the same time.

    If the ducks are not all lined up there for a chronic systemic candida infection then I don't know when else it would be.

    I am starting on Threelac as of tonight.
     
  4. JackNeedsHelp

    JackNeedsHelp Member

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  5. Dr. John Crisler

    Dr. John Crisler Lord of the Forum Staff Member Super Moderator

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    It's been an internal debate for me as to whether the PFS guys should be on a TD (giving much more DHT) or test cyp (much less DHT conversion).
     
  6. Paulo

    Paulo Banned

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    Please disregard what I originally had posted here. The only thing worth noting is that if epithelium is negatively affected by direct 5AR inhibition like it is with accutane, the choroid plexus epithelium which is responsible for endogenous production of transthyretin could be damaged as well, and if this affects retinol levels in the brain, it could result in retinoic acid deficiency and disruption of plasticity. Just a theory.
     
    Last edited: Feb 5, 2013
  7. vincentv

    vincentv Member

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    Any one offer any comments?

    I am still messed up from taking fin for 5 weeks about 5 years ago.

    Done lots of tests and taken lots of hormones.

    I have recovered mostly with anti estrogens but this does not last and can make me sick and feel like crap.

    But importantly i rediscovered my libido on them which i thoght was 6 feed deep. Also on test and anti estrogens I was able to improve strength - Test alone did not help. I increased leg exercises by 30 percent in a week.

    My blood tests show on trt when i get my free t into range my siliva estrogens go over range. This would probably explain why on trt alone I feel worse after a week.

    The question is where is this estrogen coming from. Once when I was taking erase. I got this pain in my left nut right on a little nodule on my nut. This made me wonder when this nodule came along i am sure i did not have it growing up so did it occur on finasteride? I did an ultra sound and nothing seemed to show up but it seems they focused mostly on a cyst above my testicle which I have had forever and has never been a problem.

    Is it possible that the almost total deprivation of DHT caused some issue with the process that maintains testicular health and as a result my testicles are producing too much estrogen? This is why TRT alone does not work to build muscle and cut the love handles I grew after taking finasteride?

    If it was simply an issue with peripheral aromataze you would assume that the results obtained by taking an anti estrogen would be stable. But as far as I know, anti estrogens can not really inhibit all the estrogen creation in the testicles and the other factor is that an increased LH may result in even more estradiol.


    I was on trt a few times. Last time I quit with no pct or hcg. It was hell. ALL my PFS symptoms got many times worse. I am lucky i did not jump of a cliff then. Things improved to my messed up norm in about 2 months. But it showed my PFS is androgen related.

    So do you think it is possible my nut or nuts are to blame for this? What can I do? Biopsy? Chop them off? I read testicular cancer survivors can live without problems with 0 or 1 nuts.

    If the estrogen is coming from somewhere else - where is that? Why can;t I inhibit it in a stable manner?

    Is there any thing else that could stop test from building muscle apart from too high estradiol?
     
  8. tom1989

    tom1989 Guest

    Thanks for your sharing. Maybe these will helpful for me.
     
  9. junk2222yard

    junk2222yard New Member

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    Can you elaborate on the safe alternatives for lowering DHT?

    (I am hoping I don't have to wade through 50+ pages to find that info. :))
     
  10. krx

    krx New Member

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    Hello to all. First of all sorry for my bad english, but english is not my mother language therefore I am trying my best.

    I am 19 years old, 176 cm , 70 kg.

    I've been taking the drug finasteride for 2 years against hairloss and took my last pill in November 2012. Unfortunately I developed something called "Post-Finasteride-Syndrom" - nobody really knows what it is, but you develop symptoms like hypogonadism ( I've never used ROIDS) :

    NO Errections , no sex possible ( no spontaneous,morning,nocturnal, only after physical stimulation he gets kind of hard.even not after taking 10mg Cialis)
    low - no libido
    testicle shrinkage
    big decrease in ejaculate.
    ejaculate is not"jumping" out, just fleeding out slowly ( sorry for details)
    decreased body hair

    I've been to two different doctors, the first one just made a hormon test, and all my values are in the big, wide normal range, so he says it is a psychological thing, then I've been to the second one, I just brought my whole stuff, he watched at it, just realized that he could not make any easy money with me and said : I've no experience in that case, just go to a hospital. ( I mean wtf ?.)


    Soo, I just added my current hormon values, and here are those from 2 years ago,when everything was fine

    As you can see, my Oestrogen decreased by 50 %.
    my Testo decreased by 10 %
    my Androstendion decreased by 30 %
    my DHEA'S decreased by 34 %
    my SHBG increased by 21 %
    my 17-OH-Progesteron increased by 28 %
    my FAI ( Free Androgen Index) decreased from 85 to 63. which means 26 %.

    I think this might be kind of a change - what medication would you recommend me ( I will consult another doctor anyways, but I need to give hime some direction where I want to go.

    My first thought was a HTPA re-start with hcg ,tamox,dhea supplementation and clomiphen, which could look like this :

    HcG:
    first 16 days - 2.500iu eod
    Clomid:
    50mg ed for 45 days
    Tamoxifen :
    20mg ed for 45 days.
    DHEA
    50mg. ed for long time.

    What do you think ?

    An other way could be a drug which sensitizes the androgen especially the DHT receptor, is there anything out which could do this ?

    I really hope for an answer

    Best & kind regards
     
  11. Picton

    Picton Super Moderator Staff Member Super Moderator

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  12. JohnnyS

    JohnnyS Banned

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    Not sure if it was this, but used Finasteride for a few months several years ago and now I have developed an autoimmune issue. No one in my family on any side has this. Is this possible or I am just grasping at straws??

    John
     
  13. thx

    thx Member

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    I haven't seen anything suggesting autoimmune while searching on Medline. But it might be worth self-treating with prednisone just to see if there's an effect. Right now I'm trying deprenyl but getting a little tired of the constipation.

    crvc
     
  14. Dr. John Crisler

    Dr. John Crisler Lord of the Forum Staff Member Super Moderator

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    I talked to Dr. Shippen last Saturday. He told me he is helping his PFS guys by prescribing FSH for them. This increases ejaculate volume, and so brings sexual benefits.

    If memory serves, he gets it from a place called Compounding Innovations. Someone might like to check on this.
     
  15. Dr. John Crisler

    Dr. John Crisler Lord of the Forum Staff Member Super Moderator

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    I wouldn't throw off the whole system by using a powerful corticosteroid.

    We are trying to normalize things.

    Maybe Low Dose Naltrexone (LDN)?
     
  16. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

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    http://innovationcompounding.com/for-physicians/mens-health.html

    I have no idea what the final product is called, or what they are using to compound it. I would assume factrel?
     
  17. mes6890

    mes6890 New Member

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    Hi all,

    I am new to this forum. As a woman who did not take finasteride, I am unable to join PropeciaHelp. And that's okay.

    But I have taken saw palmetto and Accutane with cataclysmic results - brain fog and cognitive sluggishness as well as complete sexual dysfunction. Accutane brought on severe and ongoing depression and also has thinned out the skin on my entire body - face, eyelids, hands, earlobes etc. Truly remarkable from five pills of anything.

    For roughly a month in November 2011, I took 320 mg/day of saw palmetto. More recently, I took Accutane at 40 mg/day for five days in July 2013.

    I'm not sure how many women are on this site, but I wanted to share my experience. I have written about it extensively at http://bloggingmybetterment.wordpress.com/.

    I took both of these substances for cystic acne.

    Since July, I've tried several things to fix myself, from stem cell therapy to acupuncture. I've written about all of it on the blog.

    I'd appreciate any insight you folks have to offer. If there are any women here with PFS like symptoms, especially sexual problems, I'd love to hear from you.

    I am getting ready to peruse this site more now.
     
  18. drphil

    drphil Member

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    Just a point about the daily Cialis. I tried this a year ago after reading articles relating to the benefits from low dose daily use. In about a week I developed SEVERE lower back ache. Discovered that this was a "possible" side effect....so stopped but thought this might be a coincidence. A month later I started it again....and again developed a horrible back ache. These pains were severe. I'm not a person who normally has back aches but I know what a normal strain feels like....having had a few over the years...but the pain is a different kind of pain. Now I note that anytime I just take one of the normal dose Cialis....I start developing some lower back pain. So, there may be benefits to daily PDF, but you can develop lower back pain.....and this is not normal back ache pain....it is really bad to the point that one cannot even sleep. Just an FYI.
     
  19. Peabody

    Peabody Member

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    In the current issue of the LEF magazine, William Falloon strongly recommends widespread use of Avodart and Proscar by men to prevent prostate cancer. Putting it in the drinking water, in effect. Not word about PFS or any side effects at all.
     
  20. Dr. John Crisler

    Dr. John Crisler Lord of the Forum Staff Member Super Moderator

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    This is a rare side effect.
     

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