1. Welcome to the All Things Male Forum. Please sign up and join the conversation. It's free!

Oxytocin 2mg For Female With Low Libido

Discussion in 'Female Health & HRT' started by Charles Risner, Dec 9, 2014.

  1. Charles Risner

    Charles Risner New Member

    Joined:
    Dec 9, 2014
    Messages:
    4
    Likes Received:
    0
    Hello,

    I am new here, and this is my first post.

    My female companion has very low libido as well as social anxiety, so she found some Oxytocin 2mg online. It has yet to arrive, though I suspect it is an injectible form. My question is, how do I transform the liquid into a dosable form for her (assuming you don't just inject it as is, the way you do with other hormones), and how much does she take per day for improved sexual function?
     
  2. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    (1 IU = 2.2 micrograms) oxytocin (please double check)
    2mg = 2000.0µg
    Vial of Oxytocin 2mg powder 2mg(Milligrams) = 2000.0µg(Micrograms)
    Usually 1mg peptide powder is mixed with 1mL of Bacteriostatic water.
    2000/2.2=909iu
    Using insulin syringe (preferably 3/10ml with 31Ga)
    1mL=100units
    one tick=9.09IU=~9iu
    two ticks=18iu
    three ticks=27iu
    four ticks=36iu

    When starting injections, usually the easiest is to inject around navel, 2-4" from navel.
    Also, it may be easier to inject somewhat larger volume, then mix powder with 2 ml of BW, then she would double the volume to get the desired amount of oxytocin.

    Some people, rarely are allergic to preservatives in BW.
    It may be worthwhile to do one injection with only BW and observe any reaction.
    She may use 10iu, ten ticks on syringe, 0.1cc for that purpose.
    ---------------------------------------------------------------
    From dr Hertoghe book, page 99
    (subqutaneous)
    Sexual activity (high value) (10-20)IU/day 2 hours before sex)
    Fibromyalgia (high value) (10-40)IU/day 2x/day
    Social binding ---- not indicated
    ----------------------------
    From compounding pharmacy, sublingual(high value), slow released(medium value)
    social binding (5-10)IU morning & evening
    sexual activity (5IU/day morning, (5-10)IU 2 hrs before sex
    Fibromyalgia (5-40)IU in 2-3 divided doses (morning, lunch, diner)
    breast feeding (10-30)IU/day
    -----------------------------
    Labor delivery
    Intravenous (3-30)IU
    -----------------------------
    More severe deficiencies, subq or IM may do better than oral or sublingual
    -----------------------------
    frequent sex, frequent social encounters, autism, schizophrenia----- require higher doses of oxytocin. Increase temporarily daily doses from 25% up to 100% of normal dose.
     
    Last edited: Dec 9, 2014
  3. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    If she goes thru with this project, please report on experience.

    Good luck.

    /

    Many reasons for low oxytocin.
    low estradiol
    low testosterone
    high cortisol, when supplementing do not overdose
    marihuana and other
    low calorie diet
    avoid living alone
    avoid agressive people
    avoid being hit or harmed
    avoid alcohol, grains, gluten, caffeinated drinks
    avoid intensive and or chronic stress


    /
     
  4. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

    Joined:
    Sep 2, 2011
    Messages:
    3,809
    Likes Received:
    123
    Assuming that it's from a reliable source.

    Injectable oxytocin has a very short half life of 1-2 hours, so your window of opportunity is small. Also, this drug is used to start uterine contractions in women to induce labor, so I would urge some caution in the dosage.

    I doubt that it is the injectable form however unless it's prescribed by a physician, if it were you would not likeley be asking about the doseage.

    The other two forms are a nasal spray or a troche. Both of these delivery methods have a much shorter half life and are not as strong as the injectable form. Either way, if you are planning on using this for sexual purposes only it's only going to be effective if used about 20-30 minutes prior to sex.

    There are other methods to treat female sexual anxiety.
     
  5. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    Oxytocin related topics:
    Postpartum depression and other.
    http://en.wikipedia.org/wiki/Postpartum_depression
    Having available oxytocin when need is important for sex and social life.
    There are also other reasons.
    There is number of reasons listed on wiki and other places, but some stuck in my mind more.
    suicide, killing own children, babies and older.

    My conclusion is that person with naturally low oxytocin should be aware of this possibilities and should always have stash of oxytocin in her/his possession and should newer run out of it.
    Having caring mate and family is important, but in the end we are all responsible for our own behavior. Person with naturally low oxytocin happens to have heaver burden that someone with average levels.

    .
     
  6. Charles Risner

    Charles Risner New Member

    Joined:
    Dec 9, 2014
    Messages:
    4
    Likes Received:
    0
    Thank you first off for the helpful replies. I too am assuming it will be in the powder form. I picked up some syringes and Bac water, and am now awaiting the arrival of her order.

    If this is injectible, how long will the mixture last before needing to be discarded, and does it require refrigeration once mixed?

    Assuming she has a response to it, what noticeable physical reactions should she immediately look for?

    When used for sexual purposes, will it be a fairly obvious/stark change, where it is clear the Oxytocin has taken effect, or does it have a slow and steady change in her sexual response?

    I will post all updates and dosages used. Any additional information and shared experiences is appreciated.
     
  7. davidrn

    davidrn Member

    Joined:
    Feb 1, 2012
    Messages:
    214
    Likes Received:
    6
    You didn't give a great deal of prior medical hiostory. My first question, related to libido is other meds taken, there is a significant history of anti depressants reducing libido, but BP meds and other meds can also have issues. Is there an MD, or other Med Prof. involved in your plan?
     
  8. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    If it is injectable, keep the vial in refrigerator.
    Put the vial in some container first to prevent food falling on it (contamination).
    I do not have idea how long reconstituted powder last, but will tell you about my 3-4 years long experience with another peptide, MT-2 (Melanotan-2).

    Melanotan II
    10mg --- powder
    2mL--- BW
    5mg/ml density of solution
    10units=0.5mg each injection (20 injections from one vial), there is a waste, more likely last injection is short or I just get 19.

    Each vial have 10mg powder.
    I use it to get darker suntan. Unfortunately, other than very first injection, it does not affect me in sexual way.
    I am starting my injections usually in January. Last injection about in August.
    Use about 1.5 vials per year.
    The remaining vial I use in following year.

    .........
    Note, my MT2 injections are have rather high volume (10 units), easier to manage.
    In your case we are talking 1, 2 possibly no more than 5 units.
    This is much harder to manage accurately.
    But,
    do not worry much about wasting one or two injections, more important is to hope that they would help.

    ...
     
    Last edited: Dec 10, 2014
  9. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    There is a chapter called:
    contraindications to oxytocin treatment in men.

    I do not see similar chapter for women.

    For men:
    Absolute contraindication for subcutaneous or intravenous administration:
    individuals who have allergic reaction to a first trial of oxytocin in the office (have adrenal schots ready in the office). The allergic reaction is rare, but may require an injection of adrenaline.
    Relative contraindication:
    patients with untreated cortisol deficiency- as oxytocin may decrease cortisol levels
    Patients with vassopressin excess (rare) as they retain water and may not tolerate the moderate water retaining effects of high dose of oxytocin.
    Do not administer oxytocin to a man before driving car or any other high risk activity, may increase drowsiness, decrease concentration (much less in women)
    Oxytocin may temporarily increase prostate volume.
    May shorten time to ejaculation.

    .....
    How to start.
    Start low, (2.5 - 5)iu/day
    then go up

    I think for the first vial you should try to use as much BW as you are able, so it is possible to to do smaller doses.

    ...
    Progress with oxytocin.
    May quickly help patient.
    Sociability may improve within 5-10 hrs after taking first time.
    May work for ejaculation in the evening after (5-10)iu morning and evening dose.
    Effects are better when taken regularly.
    Coffee and alcohol oppose the effects.
    --------------------------------
    To naturally enhance oxytocin:
    Live with people we love
    Live in family
    Being touched and hugged
    Massage
    Search sexual contact, have sexual intercourse
    Singing, music
    --------------------------
    Excessive use of oxytocin may cause lowering cortisol levels.
    That in turn may cause:
    Flu like fatigue
    Allergic reaction
    irritability
    poor resistance to stress


    ..
     
  10. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

    Joined:
    Sep 2, 2011
    Messages:
    3,809
    Likes Received:
    123
    Just an FYI, I have had extensive experience in using oxytocin in both myself and my wife. For me, its a fabulous sleep aid.

    Don't expect fireworks, but depending on your wife's chemistry, the oxytocin will make her a lot more receptive and trusting for sex. Women need oxytocin for orgasmic response as well, so that should improve. The drive to have sex does not come from oxytocin, it just makes women more receptive and trusting, which is imprtant in female sexual response.

    Men are wired differently. Oxytocin makes me feel happy and comfortable, but it doesnt ignite any flames. The mechanism of orgasm and ejaculation is much different for men than women.

    I will post a study done using testosterone and buspirone to boost female sexual response and enjoyment.
     
    Last edited: Dec 10, 2014
  11. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
  12. Charles Risner

    Charles Risner New Member

    Joined:
    Dec 9, 2014
    Messages:
    4
    Likes Received:
    0
    Ok, so I received all the 2mg vials. They are indeed in powder form. I used 2ml of Bac Water in the 2mg vial. I then gave her 20iu using an insulin syringe approx 2-4 inches from her navel.

    We have tried it 3 times now, and she has noticed two things. 1) she gets a stinging/tingling sensation in the injection site for a minute or two post injection (no visible redness or inflammation however). 2) she gets a very mild headache that last for about 10-15 minutes, with onset approximately 5 minutes post injection.

    Do either of these negative side effects seem troublesome? In her opinion, they are not onerous enough to stop. She notices a 'heavy' feeling in her body, as if she is really relaxed (similar to the heaviness felt after a good massage).

    No noticeable change in sex related department. The 1-2 hour window post injection is quite large. Should she notice some sort of 'change' signaling when it is beginning to take effect, or is the relaxed/heavy feeling what she is likely to continue noticing?

    She has recently stopped her birth control, as that may be suppressing her libido, as well as making other social/environmental changes to help her social anxiety.
     
  13. hebsie

    hebsie Super Moderator Staff Member Super Moderator

    Joined:
    Apr 13, 2008
    Messages:
    3,198
    Likes Received:
    32
    ....it sounds like you sourced it form either an U/G lab or off-shore pharm. You have no concerns about it's legitimacy?
     
  14. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

    Joined:
    Sep 2, 2011
    Messages:
    3,809
    Likes Received:
    123
    No noticeable change in sex related department. The 1-2 hour window post injection is quite large. Should she notice some sort of 'change' signaling when it is beginning to take effect, or is the relaxed/heavy feeling what she is likely to continue noticing?

    Oxytocin alone isnt going to increase her libido. The "heavy" feeling she describes (relaxed) is the effect. She is likely more trusting and receptive to you at this point, but that is pretty much the extent of it's effect. It does allow a women to be in a state that orgasm is easier (or even possible for some). Increasing libido is a lot trickier. Going off of birth control will in most cases increase a womans libido. You may consider testosterone therapy along with a 5HT1a agonist, but go through a qualified physician.

    5-HT1A agonists[edit]
    Azapirones such as buspirone, gepirone, and tandospirone are 5-HT1A agonists marketed primarily as anxiolytics, but also recently as antidepressants.

    There are new drugs on the horizon based off of some recent studies that combine testosterone and a 5HT1a agonist:

    Lybrido combines testosterone with sildenafil, a PDE5 inhibitor that produces smooth muscle relaxation and allows for blood flow into the organs of arousal. Sildenafil is the active ingredient of Pfizer's Viagra, a product approved for treating erectile dysfunction. Lybridos combines testosterone with buspirone, an anti-anxiety medication. Buspirone acts on serotonin (5-HT1A) receptors, suppressing the release of serotonin into the bloodstream.

    http://www.empr.com/too-much-libido-female-sex-pill-sparks-interest-concern/article/296498/
    http://www.emotionalbrain.nl/sites/emotionalbrain.nl/files/Poels et al PBB 2014.pdf
    http://www.ncbi.nlm.nih.gov/pubmed/23130675
     
  15. JanSz

    JanSz Well-Known Member

    Joined:
    Dec 8, 2007
    Messages:
    22,134
    Likes Received:
    71
    Good post BadassBlues

    Lybrido combines testosterone with sildenafil, a PDE5 inhibitor that produces smooth muscle relaxation and allows for blood flow into the organs of arousal. Sildenafil is the active ingredient of Pfizer's Viagra, a product approved for treating erectile dysfunction.

    Lybridos combines testosterone with buspirone, an anti-anxiety medication. Buspirone acts on serotonin (5-HT1A) receptors, suppressing the release of serotonin into the bloodstream.
    ================================
    ================================
    Above reminds me that we do not know much about this lady.
    There is a good likelihood that she need Steroid Hormone Pane optimization,
    and she may be good to go.
    Add to that
    Micronutrient Panel optimization
    Thyroid Panel Optimization
    Fatty Acids Panel Optimization
    and she may be flying.

    ..
     
  16. Charles Risner

    Charles Risner New Member

    Joined:
    Dec 9, 2014
    Messages:
    4
    Likes Received:
    0
    No new updates to speak of. Although, as time goes on, her interest in sex has begun to increase, and I have noticed a difference in her ability to interact freely with people.

    In order to assess the headaches, I've taken a number of doses. I notice a warming sensation around and on my ears, and I also notice the stinging sensation when injecting the liquid. If I go slowly, say 2-3 units every 5-10 seconds, then neither of us feel any pain; it's just when it's injected too quickly. Does this information shed any light on why the injections would be painful?
     
  17. LRS1969

    LRS1969 New Member

    Joined:
    Feb 6, 2015
    Messages:
    11
    Likes Received:
    0
    Question...

    A friend is passing on a oxytocin peptide for research purposes (I just reimburse his costs). It is 25mg powdered (and from very reliable source... used in the past for both PT 141 and Oxytocin).

    Unfortunately it is in one single vial so entire 25mg would have to be reconstituted at once. Supposedly remains potent after reconstitution with bacteriostatic water for 2 months. At "research doses", that would still leave a lot of reconstituted liquid left over.

    Can a part of the reconstituted solution (will be reconstituted in 50mL BAC water) be drawn off into other vials and frozen until needed for next round - and still remain potent?

    I have received 2 contradictory replies from other sources (sites).

    One advised that, yes, you could as long as kept at -18 C or below (0 F). The other expressed some doubt due to the water becoming "microcrystalized" upon freezing and that the crystals sharp edges might damage the oxytocin (I thought the oxytocin dissolved into solution - and the powdered form can be frozen... but then I'm just a layman!).

    Thanks for any info or thoughts.
     
  18. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

    Joined:
    Sep 2, 2011
    Messages:
    3,809
    Likes Received:
    123
    Oxytocin mixed with bac is just like HCG or peptides in that it can be frozen. The sharp crystal theory is nonsense. People freeze HCG and peps for future use all the time.

    If this oxytocin is for your personal "research" and you are male, please do your homework on males and injectable oxytocin.
     
  19. rfish1966

    rfish1966 Member

    Joined:
    Dec 19, 2008
    Messages:
    579
    Likes Received:
    1
    Oxytocin has just as many applications for men, espeically metabolic disease. Diet, metformin and victoza dropped my a1c barely 1 point in 6 months. 3 months of oxytocin 30 units, twice a day dropped it over 3 points. There are over 200 active studies and most have to do with metabolic disorders....I do take a tablet that bypasses the gut and get absorbed through the lymphatic system.
     
  20. BadassBlues

    BadassBlues Super Moderator Staff Member Super Moderator

    Joined:
    Sep 2, 2011
    Messages:
    3,809
    Likes Received:
    123
    A tablet or a troche? A troche is a sublingual.
     

Share This Page

  1. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
    By continuing to use this site, you are consenting to our use of cookies.