1. Welcome to the All Things Male Forum. Please sign up and join the conversation. It's free!

The Optimal Indication For Testosterone Replacement Therapy In Late Onset Hypogonadism.

Discussion in 'Scientific Studies' started by pubmed: testosterone, Feb 10, 2019.


  1. The Optimal Indication for Testosterone Replacement Therapy in Late Onset Hypogonadism.

    J Clin Med. 2019 Feb 07;8(2):

    Authors: Shin YS, Park JK

    Abstract
    : The use of testosterone replacement therapy (TRT) for late-onset hypogonadism (LOH) is increasing every year; however, the literature shows that many men are using testosterone (T) without a clear indication. Previous studies have estimated that up to 25% of men who receive TRT do not have their T tested prior to initiation of the therapy. Given the growing concern and need for proper TRT, clinicians need evidence-based information that informs them on the optimal indication for TRT in LOH patients. The diagnosis of LOH requires the presence of characteristic signs and symptoms, in combination with decreased serum total testosterone (TT). Based on the recent guidelines by the International Society for the Study of Aging Male (ISSAM), the European Association of Urology (EAU), the European Society of Endocrinology (ESE), the European Academy of Andrology (EAA), and the American Association of Urology (AUA), a TT of 250⁻350 ng/dL is the proper threshold value to define low T. The optimal indication for TRT in LOH is the presence of signs and symptoms of hypogonadism, and low T without contraindications for TRT.

    PMID: 30736442 [PubMed]

    Continue reading...
     

Share This Page

  1. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
    By continuing to use this site, you are consenting to our use of cookies.