Page 1 of 2 12 LastLast
Results 1 to 15 of 17
  1. #1
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Congenital adrenal hyperplasia (CAH)

    http://www.mlcull.demon.co.uk/PDFs/C...umns%20New.pdf
    ..
    http://www.mlcull.demon.co.uk/index.htm

    What is Congenital Adrenal Hyperplasia?


    The 3 main steroids involved in CAH are:

    · Cortisol controls how the body copes with stress, emotional and physical, such as infection or injury. It also helps to control blood sugar levels, raising these levels if they become too low particularly in children.

    · Aldosterone helps to regulate the salt levels in the body. Aldosterone causes the kidneys to conserve salt if there is too little salt in the diet, or if a lot of salt is lost due to excessive sweating. Conversely, if a lot of salt is eaten the adrenal cortex reduces the amount of aldosterone secreted, allowing the excess salt to be passed in the urine.

    · Androgens are a group of male hormones, one of which is testosterone. For the rest of this booklet the term testosterone will be used to refer to the androgen group. Testosterone is produced by the adrenal cortex in both males and females and they control the formation of pubic hair at the onset of puberty. Testosterone is also produced by the testis and in small amounts by the ovary.

    There are five main enzymes in the adrenal gland which convert cholesterol into the important steroid cortisol. If any of these enzymes are missing or defective then not enough cortisol is made for the needs of the body. The body, recognising the low levels of cortisol, will try to stimulate the adrenal cortex to make more by ‘pushing’ the gland harder by a stimulating

    hormone called ACTH made in the pituitary gland. The constant unsuccessful stimulation causes the cortex to increase in thickness and become ‘hyperplastic’.



    http://img258.imageshack.us/img258/9076/image1jz.jpg
    In the most common form of CAH there is a deficiency of an enzyme called 21 hydroxylase. In this form of CAH the production of cortisol and aldosterone is low while testosterone, the male hormone, is produced normally. As the body pushes the adrenal gland harder trying to correct the low cortisol level more and more testosterone is made. In boys, this excess of testosterone causes early sexual development. In females, the excess in testosterone can cause abnormal genital development before birth while in adults it causes irregular periods, unwanted hair growth and acne. Only by correcting the levels of cortisol with substitute therapy does the body recognise normal levels and stop producing excessive amounts of testosterone and the circulating levels become normal.

    The hormone disturbances caused by CAH:

    Lack of cortisol

    Lack of aldosterone

    Excessive androgens

    ////////////////////////////////////////////////////////////////////////
    http://www.mlcull.demon.co.uk/different_types_cah.htm
    Different Types of CAH

    There are many different grades of severity of CAH depending on the degree of impairment of production of cortisol and aldosterone. In the most severe type of CAH aldosterone is completely lacking and loss of salt from the body is the most prominent problem – salt losing CAH accounts for 80% of children with CAH. The loss of salt in the urine is uncontrolled and can cause acute dehydration, very low blood pressure and vomiting. The levels of salt (sodium and chloride) and sugar (glucose) fall in the blood, and the potassium level rises. This is an ‘Adrenal Crisis’ needing very urgent treatment as a potentially life threatening condition.

    In the 20% of children with less severe CAH, non salt-losing CAH, the salt balance is normal. In stressful situations, however, some people with non-salt losing CAH may become salt losers and need extra treatment. Girls born with non salt-losing CAH are usually healthy, but often born with an enlarged clitoris and the labia may be partially fused because of the excess of testosterone. In boys, non salt-losing CAH produces no detectable signs at birth and the diagnosis is made when the penis enlarges at a very early age along with early pubic hair and rapid growth in height the result of high levels of testosterone. These changes may not occur until 4 or 5 years old.

    The mildest form of CAH – late onset CAH - affects women at any age. Symptoms of unwanted hair growth or irregular periods can start at any time after puberty. Often treatment with steroids is not necessary in women with late onset CAH. Instead, giving oestrogen as in the oral contraceptive can regulate testosterone from the ovary. In fact, the treatment of late onset CAH is usually the same as for the polycystic ovary syndrome because the two conditions are so similar. In men, late onset CAH usually goes unrecognised although it may cause the sperm count to be low.

    All of the types of CAH above are deficiencies of the enzyme 21 hydroxylase which account for over 90% of people with CAH. The next most common deficiency is of the enzyme 11-beta hydroxylase. Treatment of this type of CAH is more complicated because high blood pressure can be severe if treatment inadequate. The balance of treatment in 11-beta hydroxylase deficiency is very difficult and an experienced specialist is essential. Deficiencies of other enzymes are exceedingly rare and beyond the scope of this pamphlet. A specialist will be able to offer more information on the rarer forms of CAH. Adrenogenital syndrome is an older name for CAH which is still used occasionally.

    //////////////////////////////////////////////////////////////////////////
    http://www.mlcull.demon.co.uk/treatment_cah.htm
    Treatment of CAH
    People with CAH have a normal life expectancy and for most people there is very little interference in every day life if the condition is well managed. Adults with CAH require life long follow up in specialist hospital clinics in order to maintain the correct level of medical care and to provide early advice on fertility when needed.

    It is advisable to have regular medical checks even if everything is well controlled. For women, checks should be made 2 - 3 times per year. For men, once per year is usually sufficient. The main aim of treatment is to maintain normal cortisol levels and control of salt loss, in those who are salt losers. In women, good management of CAH brings about control of testosterone levels, regular periods and improved fertility. In men, good management can reduce an aggressive behaviour and control excessive libido. Also, the sperm count can fall if CAH is not well treated and an increase in the dose of steroid treatment for some months can restore fertility in men.

    Replacement of cortisol

    The object of cortisol treatment in CAH is to replace inadequate production of cortisol by the adrenal glands allowing the body to recognise normal levels of cortisol in the body, which reduces the need for the adrenal gland to produce excessive amounts of testosterone.

    How do doctors work out how much cortisol to take?

    If the cortisol dosage is too low the adrenal gland will try and make more, but only succeed in making more testosterone. The effect of these excess androgens is growth of body hair in women and infertility in both sexes. In severe forms of CAH, too little cortisol treatment may make the body unable to cope with stress and infection, so that major surgery or an illness like ‘flu’ can be life threatening. If the dose of cortisol treatment is too low, a blood test will establish this by showing high levels of several adrenal hormones of which the most commonly measured are:

    17 Hydroxyprogesterone

    Androstenedione

    Testosterone


    Other side effects of steroid treatment are:

    Headaches (sometimes associated with taking prednisolone and dexamethasone)

    Feeling sick / nausea / tiredness

    Finding it difficult to cope with stress

    Water retention (sometimes associated with taking Hydrocortisone and Cortisone acetate)

    There are four types of cortisol replacement treatment: Hydrocortisone, Cortisone acetete (now rarely available in the UK), Prednisolone and Dexamethasone. They vary in their dose and duration of action. Hydrocortisone is another name for cortisol. Prednisolone is 5 times more potent, and dexamethasone is 40 times more potent than cortisol. Both prednisolone and dexamethasone are comparatively long acting, where as cortisone acetate and hydrocortisone are shorter acting, and need to be taken 2 to 3 times a day. The dose in each dexamethasone tablet is not convenient for fine-tuning of treatment leading to a danger of taking too high a dose. Dexamethasone is established for use in pregnancy for women who are at risk of having a child with CAH. Hydrocortisone is also used as an injection at times of adrenal crisis or when vomiting prevents the tablets from being taken.


    continued on next page......
    Last edited by JanSz; 12-23-2010 at 11:25 AM.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  2. #2
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    cont from previous page......
    Variety of steroid tablets and examples of the range normal daily doses.
    The exact dose needed each day for each individual will differ, due to the variation in body size, different rates of absorption in the bowel. It is important to assess the individual response, taking into account timing of the day that medication is taken. It is important to be clear how many tablets are missed so that the correct balance of dosage can be achieved. Many people find it difficult to take tablets regularly and this can lead to conflict with doctors.

    At times of stress such as during illness or physical or emotional shock, the dose of cortisol replacement treatment should be increased in a controlled way. The exact regime should be agreed in prior discussion with you doctor. For example, a double or treble dose is usually advised at times of stress. The body increases cortisol in situations of high mental stress and it may therefore be necessary to give an increased dose even if only for one day for exams, a driving test, or a sudden bereavement for example. If an illness causes prolonged vomiting which prevents tablets from being taken, then an injection of hydrocortisone 100 mg should be given into the muscle and a doctor should be called. The technique of injection can be learnt by members of the family with instruction from the practice nurse.

    Unless there has been substantial over dosing of fludrocortisone, blood pressure should not present a problem taking into account the wide variation in general blood pressure levels.


    Replacement of aldosterone

    All individuals with salt losing CAH need to replace the lack of aldosterone. Only one form of treatment is used here. Fludrocortisone is given in a dose of 50 – 300 micrograms. Too little fludrocortisone can cause low blood pressure and dizziness. Too much fludrocortisone can cause high blood pressure and headaches. The correct level of fludrocortisone is determined by measuring blood pressure, potassium and the salt sensitive hormone renin in the blood every few years.

    //////////////////////////////////////////////////////////////////////////////////
    http://www.mlcull.demon.co.uk/issues_both_cah.htm
    Issues for Adults with CAH - Men and Women

    The problem of being over weight

    Many people with CAH, women in particular, have a battle to avoid gaining weight. Mostly, weight gain in CAH is a side effect of treatment with hydrocortisone, prednisolone or dexamethasone and to a lesser extent, the oral contraceptive pill if used. Short stature and depression can also make weight gain more likely. Careful monitoring of weight is important as prevention of weight gain is better than a harsh weight reducing diet. Careful adjustment of treatment and attention to diet and exercise should enable most people with CAH to avoid obesity. A normal healthy diet which is low in sugar and fat and high in fibre is best. A sugar craving can be hormone driven although the effect of various treatments is unpredictable. Regular sustained exercise of an hour several times per week may be required to keep fitness levels up and weight down.

    What should my weight be? Doctors use an equation called the body mass index or BMI to work out how heavy you should be for your height. Your BMI is your weight in kilograms divided by your height squared - wt/ht/ht. The normal range of BMI is 20 to 25 kg/m2. The next figure shows the normal range for BMI.
    ////////////////////////////////////////////////////////////////////////////////////////

    http://www.mlcull.demon.co.uk/issues_male_cah.htm
    Issues for Men with CAH
    The problems of weight gain and the side effects of treatment can affect men as much as women. Short stature, which can result for difficulties in treatment of CAH in childhood, can be a particular psychological burden for men. High levels of testosterone in CAH can cause problems with aggression and excessive sex drive in men.

    There are two important long-term consequences of CAH which only affect men, both of which are the result of too little treatment with cortisol. These are infertility and testicular enlargement. If adrenal suppression is inadequate then the adrenal gland makes too much testosterone. High testosterone production from the adrenal gland can occur because the dose of cortisol is too low or because tablets have been missed. The testicles, which also make testosterone, then shutdown as the testosterone levels are high. Unfortunately, 'shutting down' the testicles also means that sperm are not produced in normal quantities and this can cause infertility. Sperm production usually picks up if the adrenal cortisol treatment is increased allowing the testosterone production from the adrenal glands to fall, so the testicles can begin to work again. It can take several months the sperm count to rise after an increase in steroid treatment.

    Testicular enlargement is a rare effect of under dosage of cortisol treatment and it takes many years of inadequate treatment for this to occur. Normal testicles contain a few adrenal cells that enlarge if the levels of cortisol in the body are low. This enlargement usually goes away if the dose of cortisol treatment is increased. Occasionally doctors advise a biopsy of the enlarged testicle to make sure that there is no hidden cancer. CAH does not cause cancer but it is reassuring to make this check.

    //////////////////////////////////////////////////////

    http://www.mlcull.demon.co.uk/medical_advisors_ahn.htm

    Medical Advisors
    Dr Gerard Conway - Consultant Endocrinologist, (London)
    Dr Richard Stanhope – Consultant Paediatric Endocrinologist, (London)
    Miss Sarah Creighton – Consultant Obstetrician & Gynaecologist, (London)
    Dr Catherine Minto – Clinical Research Fellow Gynaecology, (London)
    Dr Lih-Mei Liao - Consultant Clinical Psychologist, (London)
    Dr Julie Alderson – Consultant Clinical Psychologist, (Leeds)
    Mr Adam Balen – Consultant Obstetrician & Gynaecologist & Sub-Specialist in Reproductive Medicine, (Leeds)
    Mrs Kathryn May – Clinical Sexual Psychologist, (Lancashire)
    Mr Kevin Hobbs – Clinical Sexual Therapist, (Lancashire)
    Professor Peter Hindmarsh – Consultant Paediatric Endocrinologist, (London)

    ==========
    ////////////////////////////////

    http://www.mlcull.demon.co.uk/person...ries_ahn_3.htm
    Personal Stories - Page 3


    http://www.mlcull.demon.co.uk/links_ahn.htm
    CAH Support Group Links

    http://www.mlcull.demon.co.uk/copyright_ahn.htm
    Copyright
    The Adrenal Hyperplasia Network (AHN) grants permission for the browsing of material it has published on its Web Site pages. It also grants permission for the downloading and printing of one copy only of any page of this material for personal reference only. Copyright in all material on this Web Site (unless otherwise indicated) is held by the Adrenal Hyperplasia Network. The express permission of the Copyright holder must be obtained for any use of this material other than for purposes permitted by law.

    http://www.icd9data.com/2011/Volume1.../255/255.2.htm


    ////////////////////////////////////////
    http://en.wikipedia.org/wiki/Congeni...al_hyperplasia



    =================================
    =================================
    Originally Posted by CubbieBlue
    http://allthingsmale.com/forum/showp...2&postcount=16


    http://www.caresfoundation.org/produ...onset_cah.html

    Non-classical Adrenal Hyperplasia

    Non-classical(NCAH) (also known as Late-Onset CAH) is a variation of CAH that can begin to cause noticeable changes at any time from early childhood through early adulthood but is not immediately life-threatening.


    ..
    http://www.mazorguide.com/MazorNet/g...a.htm#Symptoms
    Non-Classical Adrenal Hyperplasia

    Last edited by JanSz; 12-23-2010 at 11:28 AM.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  3. #3
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    It starts with cholesterol.
    Who makes what?

    http://themedicalbiochemistrypage.or...-hormones.html

    There is a four places where conversion cholesterol---->pregnenolone takes place.
    Three places in adrenals:

    and Gonadal Steroid Hormones



    Last edited by JanSz; 12-16-2010 at 10:23 PM.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  4. #4
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    llllllllllllllllllllllllllllllllllllllllllllllllll lllllllllllllllllllll
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  5. #5
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    22222222222222222222222222


    Enzymes and genes involved in adrenal steroidogenesis.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  6. #6
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    Age

    Classic congenital adrenal hyperplasia is generally recognized at birth or in early childhood because of ambiguous genitalia, salt wasting, or early virilization. Nonclassic adrenal hyperplasia is generally recognized at or after puberty because of oligomenorrhea or virilizing signs in females.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  7. #7
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    999999999)))))))))))))))))))))))
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  8. #8
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    http://emedicine.medscape.com/article/919218-overview


    More on Congenital Adrenal Hyperplasia

    Overview: Congenital Adrenal Hyperplasia
    Differential Diagnoses & Workup: Congenital Adrenal Hyperplasia
    Treatment & Medication: Congenital Adrenal Hyperplasia
    Follow-up: Congenital Adrenal Hyperplasia
    Multimedia: Congenital Adrenal Hyperplasia
    References
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  9. #9
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    http://emedicine.medscape.com/article/919218-treatment
    Hydrocortisone (A-Hydrocort, Cortef, Hydrocort)

    Same as cortisol, which is the primary steroid hormone secreted by adrenal zona fasciculata and reticularis. DOC in children due to short half-life and decreased potential for growth suppression. Mineralocorticoid effect at large doses.
    Adult
    25-35 mg/d PO/IV/IM divided in 2-3 doses; dose doubled or tripled under stress conditions

    Pediatric
    10-15 mg/m2/d PO divided tid; dose doubled or tripled under stress conditions

    interactions
    Phenytoin, phenobarbital, ephedrine, mitotane, and rifampin may increase the hepatic clearance of corticosteroids; coadministration with anticoagulants may prolong PT; potassium-depleting diuretics may enhance hypokalemia

    contraindications
    Documented hypersensitivity; viral, fungal, or tubercular skin infections
    ======
    Fludrocortisone acetate (Florinef)

    Synthetic steroid with predominantly mineralocorticoid activity. Acts on renal tubule to promote sodium retention in exchange for potassium or hydrogen ion and thus maintain intravascular and extracellular volume. For patients who require parenteral mineralocorticoid therapy, high-dose hydrocortisone must be used. Available only as tab; may be crushed for infants and children.

    Adult
    0.05-0.2 mg/d PO

    Pediatric
    Administer as in adults

    Precautions
    May cause sodium retention, hypokalemia, or hypertension; caution in patients with hypertension or patients taking potassium-depleting diuretics or digoxin; gradually taper when discontinuing
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  10. #10
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    7777777************&&&&&&&&&&&7
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  11. #11
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    Follow-up

    Further Outpatient Care

    Closely monitor patients with adrenal hyperplasia for adequacy of dosing of glucocorticoids, mineralocorticoids, or both.

    Too little glucocorticoid results in symptoms of adrenal insufficiency (eg, anorexia, nausea, vomiting, abdominal pain, asthenia) and progressive virilization and advancement of skeletal maturation in virilizing forms.
    Too much glucocorticoid results in excess weight gain, Cushingoid features, hypertension, hyperglycemia, cataracts, and growth failure.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  12. #12
    Join Date
    Jul 30, 2009
    Posts
    1,216
    Rep Power
    7

  13. #13
    Join Date
    Dec 08, 2007
    Location
    New Jersey USA
    Posts
    21,168
    Rep Power
    28

    Default Re: Congenital adrenal hyperplasia (CAH)

    Quote Originally Posted by Dadoo View Post
    My interest for CAH stopped, after I found out how the real CAH patients look like - definitely not my story, has nothing to do with my problems, watch this

    http://www.youtube.com/watch?v=0gABZn7T5zA&t=0m38s
    I am not after proving that CAH does not apply to most of our members.

    CAH results in deficiency of cortisol and aldosterone.

    This is what we all (or most of us) have in common with CAH.

    It is worth to see how CAH is studied, may help others who have just "plain" cortisol &/or aldosterone defficiency.

    The treatment of CAH is plain vanilla (HC + Florinef).
    People with CAH have not much of other choices,

    most of us do have better choices (we would like to think).




    ///
    Last edited by JanSz; 12-06-2010 at 04:54 PM.
    I am not a Dr, any opinion that I have is based on my own experience.
    Any changes in my regime are always discussed with and are approved by my doctor.

    Diabetes is not a disease. It is how mammals signal for the coming winter. You can cure it naturally.
    ...all legitimate rights have one thing in common: they are rights to action, not to rewards from other people."
    Failure is the spice that gives success its flavors………….If you don’t do the fear, you won’t get the courage.

  14. #14
    Join Date
    Feb 20, 2008
    Posts
    7,759
    Rep Power
    14

    Default Re: Congenital adrenal hyperplasia (CAH)

    Quote Originally Posted by Dadoo View Post
    My interest for CAH stopped, after I found out how the real CAH patients look like - definitely not my story, has nothing to do with my problems, watch this

    http://www.youtube.com/watch?v=0gABZn7T5zA&t=0m38s
    You're correct about CAH. It's a medical term which is only used to describe a life-threatening condition.

    Your issue is that you have a 3βHSD enzyme deficiency, but it's not zero.

    The medical definition of CAH is when 3βHSD is effectively zero.

    Therefore your situation is that you have a genetic anomaly, but it's not in the life threatening category, which means you're not able to be classified as CAH, but you're nowhere near normal either.

    A 3βHSD enzyme deficiency, as serious as yours, is statistically rare. It's not as rare as the life threatening form which would classify you as a CAH victim, but it's still rare.

    .

  15. #15
    Join Date
    Jul 30, 2009
    Posts
    1,216
    Rep Power
    7

    Default Re: Congenital adrenal hyperplasia (CAH)

    Quote Originally Posted by chilln View Post
    You're correct about CAH. It's a medical term which is only used to describe a life-threatening condition.

    Your issue is that you have a 3βHSD enzyme deficiency, but it's not zero.

    The medical definition of CAH is when 3βHSD is effectively zero.

    Therefore your situation is that you have a genetic anomaly, but it's not in the life threatening category, which means you're not able to be classified as CAH, but you're nowhere near normal either.

    A 3βHSD enzyme deficiency, as serious as yours, is statistically rare. It's not as rare as the life threatening form which would classify you as a CAH victim, but it's still rare.

    .

    (sorry if I am hijacking)

    Yes I agree, I must be somewhere inbetween, not zero, but not optimal enzymes activity.

    The general reason for my health problems I guess is:

    a) my father lived in an area where atom bombs where tested -> impaired his DNA
    b) my mother had an extremely stressful life-style after moving out of the village straight to St. Petersburg, where she studied and worked at nights, for couple of years
    c) the docs damaged me with lots of different strong meds when trying to rescue me from allergy-death when I was 1 yo.

 

 

Similar Threads

  1. Replies: 0
    Last Post: 07-18-2012, 06:00 AM
  2. Replies: 0
    Last Post: 05-24-2011, 06:00 AM
  3. Replies: 0
    Last Post: 06-07-2009, 02:40 PM
  4. Replies: 0
    Last Post: 11-11-2008, 12:36 PM
  5. Replies: 0
    Last Post: 09-11-2008, 09:00 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
All times are GMT -4. The time now is 04:27 PM.